Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Dec 2;11(12):4876-901.
doi: 10.3390/md11124876.

Anticancer and cancer preventive properties of marine polysaccharides: some results and prospects

Affiliations

Anticancer and cancer preventive properties of marine polysaccharides: some results and prospects

Sergey N Fedorov et al. Mar Drugs. .

Abstract

Many marine-derived polysaccharides and their analogues have been reported as showing anticancer and cancer preventive properties. These compounds demonstrate interesting activities and special modes of action, differing from each other in both structure and toxicity profile. Herein, literature data concerning anticancer and cancer preventive marine polysaccharides are reviewed. The structural diversity, the biological activities, and the molecular mechanisms of their action are discussed.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Fucoidan from Laminaria cichorioides.
Figure 2
Figure 2
Fucoidan from F. evanescens.
Figure 3
Figure 3
Galactofucan from L. japonica.
Figure 4
Figure 4
The structures of G- and M-chains of laminarans.
Figure 5
Figure 5
Structure of alginic acid.
Figure 6
Figure 6
Structures of repeating units of some carrageenans.
Figure 7
Figure 7
Structure of the main repeating disaccharide in Ulva rigida.

References

    1. Laurienzo P. Marine polysaccharides in pharmaceutical application: An overview. Mar. Drugs. 2010;8:2435–2465. doi: 10.3390/md8092435. - DOI - PMC - PubMed
    1. Senni K., Pereira J., Gueniche F., Delbarre-Ladrat C., Sinquin C., Ratiskol J., Godeau G., Fischer A.M., Helley D., Colliec-Jouault S. Marine polysaccharides: A source of bioactive molecules for cell therapy and tissue engineering. Mar. Drugs. 2011;9:1664–1681. doi: 10.3390/md9091664. - DOI - PMC - PubMed
    1. Stonik V.A., Fedorov S.N. Cancer preventive marine natural product. In: Kwak H., editor. Cellular and Genetic Practices for Translational Medicine. Research Signpost; Karalla, India: 2011. pp. 1–36.
    1. Beress A., Wassermann O., Bruhn T., Beress L., Kraiselburd E.N., Gonzalez L.V., de Motta G.E., Chavez P.I. A new procedure for the isolation of anti-HIV compounds (polysaccharides and polyphenols) from the marine alga Fucus vesiculosus. J. Nat. Prod. 1993;56:478–488. doi: 10.1021/np50094a005. - DOI - PubMed
    1. Ponce N.M.A., Pujol C.A., Damonte E.B., Flores M.L., Stortz C.A. Fucoidans from the brown seaweed Adenocystis utricularis: Extraction methods, antiviral activity and structural studies. Carbohydr. Res. 2003;338:153–165. doi: 10.1016/S0008-6215(02)00403-2. - DOI - PubMed

Publication types

MeSH terms

LinkOut - more resources