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. 2013 Nov;156(1):94-7.
doi: 10.1007/s10517-013-2286-y.

Blood microvesicles during chronic lymphoproliferative diseases

N P Domnikova  1 , T Yu Dolgikh, E V Sholenberg, E V Vorontsova, O B Goreva, E V Mel'nikova, E A Gorbachenko, A Yu Grishanova
Affiliations

Blood microvesicles during chronic lymphoproliferative diseases

N P Domnikova et al. Bull Exp Biol Med. 2013 Nov.

Abstract

The levels of CD19 (+) and CD20(+) microvesicles were estimated in the blood of patients with B-cell chronic lymphocytic leukemia and indolent non-Hodgkin lymphoma by flow cytometry method. It was found that the number of B cell microvesicles is several times higher in patients than in volunteers. The level of CD20 (+) microvesicles directly correlated with the number of CD20(+) lymphocytes in patients with chronic lymphoproliferative diseases. Extramedullary tumors cells can be a source of CD19 (+) microvesicles.

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