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Editorial
. 2013 Dec;98(12):1819-21.
doi: 10.3324/haematol.2013.094912.

What lies beyond del(5q) in myelodysplastic syndrome?

Vera Adema  1 , Rafael Bejar
Affiliations
Editorial

What lies beyond del(5q) in myelodysplastic syndrome?

Vera Adema et al. Haematologica. 2013 Dec.
No abstract available

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Figures

Figure 1.
Figure 1.
New dimension to the spectrum of genetic abnormalities identified in del(5q) MDS and their impact on disease risk. Increasing chromosomal complexity is recognized as an adverse risk factor in del(5q) MDS. Fernandez-Mercado et al. demonstrate the molecular genetic heterogeneity of this group which include additional mutations in many genes, including TP53 which has been associated with a very poor prognosis. This may lead us to reconsider how we assess MDS patients we previously put into discrete risk categories based on cytogenetics alone.
See this image and copyright information in PMC

References

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