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Comment
. 2013 Dec;98(12):e164-5.
doi: 10.3324/haematol.2013.099077.

Impact of IKZF1 deletions on IKZF1 expression and outcome in Philadelphia chromosome negative childhood BCP-ALL. Reply to "incidence and biological significance of IKZF1/Ikaros gene deletions in pediatric Philadelphia chromosome negative and Philadelphia chromosome positive B-cell precursor acute lymphoblastic leukemia"

Chiara Palmi  1 , Tobia Lana, Daniela Silvestri, Angela Savino, Geertruy Te Kronnie, Valentino Conter, Giuseppe Basso, Andrea Biondi, Maria Grazia Valsecchi, Giovanni Cazzaniga
Affiliations
Comment

Impact of IKZF1 deletions on IKZF1 expression and outcome in Philadelphia chromosome negative childhood BCP-ALL. Reply to "incidence and biological significance of IKZF1/Ikaros gene deletions in pediatric Philadelphia chromosome negative and Philadelphia chromosome positive B-cell precursor acute lymphoblastic leukemia"

Chiara Palmi et al. Haematologica. 2013 Dec.
No abstract available

Keywords: IKZF1 deletions; copy number abnormalities; pediatric Ph- BCP-ALL; prognosis.

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Figures

Figure 1.
Figure 1.
Gene expression values for IKZF1probes 1565816_at (A) and 1565818_s_at (B) in patients with (DEL) and without (WT) IKZF1 deletions.
Figure 2.
Figure 2.
Gene expression values for IKZF1 by RQ-PCR in patients with (DEL) and without (WT) IKZF1 deletions. Boxes include 10–90 percentile, mean (internal line) and median (cross) are shown. Dots indicate outliers.
See this image and copyright information in PMC

Comment on

References

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    1. Asai D, Imamura T, Suenobu S, Saito A, Hasegawa D, Deguchi T, et al. IKZF1 deletion is associated with a poor outcome in pediatric B-cell precursor acute lymphoblastic leukemia in Japan. Cancer Med. 2013;2(3): 412–9 - PMC - PubMed
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