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. 1987 Jan;135(1):48-51.
doi: 10.1164/arrd.1987.135.1.48.

Natural course of bleomycin-induced pneumonitis. A follow-up study

P W Van Barneveld, D T Sleijfer, T W van der Mark, N H Mulder, H S Koops, H J Sluiter, R Peset

Natural course of bleomycin-induced pneumonitis. A follow-up study

P W Van Barneveld et al. Am Rev Respir Dis. 1987 Jan.

Abstract

In this study, long-term pulmonary complications of bleomycin were evaluated in 8 patients with bleomycin-induced pneumonitis (BIP). The lung function parameters: VC, alveolar volume, transfer factor for carbon monoxide of the lungs, diffusing capacity of the alveolocapillary membrane, and pulmonary capillary blood volume were studied in all patients for as long as 2 yr after the development of BIP. Perfusion scans with 133Xe and 99mTc were performed in these patients 2 yr after BIP developed. We concluded that if a patient survives the acute event of BIP, the pulmonary symptoms and the changes in these lung function parameters are completely reversible.

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