Comment
doi: 10.1016/j.chom.2013.11.012.
Streptococcus pyogenes escapes from autophagy
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- PMID: 24331458
- DOI: 10.1016/j.chom.2013.11.012
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Streptococcus pyogenes escapes from autophagy
Cell Host Microbe.
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Abstract
Autophagy is important for innate defense against intracellular bacteria, such as Group A Streptococcus (GAS). In this issue of Cell Host & Microbe, Barnett et al. (2013) demonstrate that the globally disseminated serotype M1T1 clone of GAS can evade autophagy via streptococcal cysteine protease SpeB-mediated degradation of ubiquitin-LC3 adaptor proteins.
Copyright © 2013 Elsevier Inc. All rights reserved.
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The globally disseminated M1T1 clone of group A Streptococcus evades autophagy for intracellular replication.Cell Host Microbe. 2013 Dec 11;14(6):675-82. doi: 10.1016/j.chom.2013.11.003. Cell Host Microbe. 2013. PMID: 24331465 Free PMC article.
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