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Comment
. 2013 Dec 9;24(6):691-3.
doi: 10.1016/j.ccr.2013.11.016.

A novel bullet hits the proteasome

Alexei F Kisselev  1
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Free article
Comment

A novel bullet hits the proteasome

Alexei F Kisselev. Cancer Cell. .
Free article

Abstract

An elegant paper by Anchoori and colleagues in this issue of Cancer Cell describes an irreversible inhibitor of Rpn13, one of the ubiquitin receptors on the 26S proteasome that is nonessential for proteasome function in most normal tissues, but is overexpressed in many solid tumors.

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