The evolution of tumor classification: a role for genomics?
- PMID: 24332038
- PMCID: PMC3928679
- DOI: 10.1016/j.ccr.2013.11.019
The evolution of tumor classification: a role for genomics?
Abstract
Lung cancers are divided into four types according to their histologic appearance. Therapeutic decisions are partly based on histology. A recent study indicates that certain molecular alterations associate with histology and that therapies directed to these molecular changes improve outcome, indicating that genomic information should be incorporated into future tumor classification.
Copyright © 2013 Elsevier Inc. All rights reserved.
Conflict of interest statement
Conflicts of Interest:
Paul A. Bunn, Jr. MD: None
Robert Doebele, MD, PhD: None
Wilbur Franklin: None
Comment on
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A genomics-based classification of human lung tumors.Sci Transl Med. 2013 Oct 30;5(209):209ra153. doi: 10.1126/scitranslmed.3006802. Sci Transl Med. 2013. PMID: 24174329 Free PMC article.
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