The antitumor effects of interferon
- PMID: 2433551
- DOI: 10.1007/BF02934998
The antitumor effects of interferon
Abstract
Interferons show antitumor activity in patients with various malignancies. The mechanism(s) of the antitumor effects are not altogether clear. In one experimental animal model discussed herein, mice were injected with Friend erythroleukemia cells and treated with mouse interferon alpha/beta. The results suggest that interferon does not act directly on the tumor cells but acts via host mechanisms that are still ill defined.
Similar articles
-
Antitumor effects of interferon in mice injected with interferon-sensitive and interferon-resistant Friend leukemia cells. III. Inhibition of growth and necrosis of tumors implanted subcutaneously.Int J Cancer. 1983 May 15;31(5):649-53. doi: 10.1002/ijc.2910310518. Int J Cancer. 1983. PMID: 6189790
-
Anti-tumor effects of interferon in mice injected with interferon-sensitive and interferon-resistant friend leukemia cells. IV. Definition of optimal treatment regimens.Int J Cancer. 1986 Aug 15;38(2):251-7. doi: 10.1002/ijc.2910380216. Int J Cancer. 1986. PMID: 2426208
-
Anti-tumor effects of interferon in mice injected with interferon-sensitive and interferon-resistant Friend leukemia cells. VI. Adjuvant therapy after surgery in the inhibition of liver and spleen metastases.Int J Cancer. 1987 Jun 15;39(6):789-92. doi: 10.1002/ijc.2910390623. Int J Cancer. 1987. PMID: 2438237
-
Antitumor effects of interferon.Acta Oncol. 1989;28(3):347-53. doi: 10.3109/02841868909111205. Acta Oncol. 1989. PMID: 2472822 Review.
-
Interferon and cancer: therapeutic prospects.Rev Eur Etud Clin Biol. 1970 Jan;15(1):23-7. Rev Eur Etud Clin Biol. 1970. PMID: 4910000 Review. No abstract available.
Cited by
-
JAK-STAT Signaling: A Double-Edged Sword of Immune Regulation and Cancer Progression.Cancers (Basel). 2019 Dec 12;11(12):2002. doi: 10.3390/cancers11122002. Cancers (Basel). 2019. PMID: 31842362 Free PMC article. Review.