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. 1986;66(6):527-30.

Expression of OKM5 antigen on human keratinocytes in vitro upon stimulation with gamma-interferon

  • PMID: 2433875

Expression of OKM5 antigen on human keratinocytes in vitro upon stimulation with gamma-interferon

J Hunyadi et al. Acta Derm Venereol. 1986.

Abstract

Using murine monoclonal antibodies against human OKM5, OKM1 and HLA-DR antigens antigenic characteristics of freshly separated human epidermal cells (EC) and those of EC cultured in the presence of Interferon-gamma (IFN-gamma) were studied. After 8-12 days of culture, primarily OKM1- OKM5- HLA-DR- keratinocytes displayed OKM5 and HLA-DR antigens when exposed to IFN-gamma. Our data support the concept, that human keratinocytes may possess accessory cell functions.

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