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Clinical Trial
. 2013 Dec 10;8(12):e81960.
doi: 10.1371/journal.pone.0081960. eCollection 2013.

High prevalence of illicit drug use in men who have sex with men with HIV-1 infection in Japan

Takeshi Nishijima  1 , Hiroyuki Gatanaga, Hirokazu Komatsu, Misao Takano, Miwa Ogane, Kazuko Ikeda, Shinichi Oka
Affiliations
Clinical Trial

High prevalence of illicit drug use in men who have sex with men with HIV-1 infection in Japan

Takeshi Nishijima et al. PLoS One. .

Abstract

Objective: To examine the prevalence of illicit drug use among men who have sex with men (MSM) with HIV-1 infection in Japan, where the life-time prevalence of illicit drug use in the general population is only 2.9%.

Design: A single-center cross-sectional study at a large HIV clinic in Tokyo, which treats approximately 15% of HIV-1 infected patients in Japan.

Methods: The prevalence of illicit drug use and the association of characteristics and social demographics of the patients with illicit drug use were examined. Patients who visited the clinic for the first time from 2005 to 2010 were enrolled. Relevant variables were collected using a structured interview and from the medical records. Multivariate logistic regression analyses were applied to estimate the odds of association of MSM over non-MSM HIV-infected patients with illicit drug use.

Results: 1,196 patients were enrolled. They were mostly Japanese men of relatively young age. Illicit drug use (including injection drugs) was reported by 35% of the patients (by 40% of MSM), and 4% were IDU while 5% were on methamphetamine. 2% of the population was arrested due to illicit drugs. MSM was significantly associated with illicit drug use (adjusted OR = 4.60; 95% CI, 2.88-7.36; p<0.01). Subgroup analysis of the patients stratified by three age groups (≤ 30, 31 to 40, and >40) showed that the odds of association of MSM with illicit drug use was the strongest in the youngest age group (≤ 30 years: adjusted OR = 7.56; 95% CI, 2.86-20.0; p<0.01), followed by the oldest (>40 years: adjusted OR = 6.15; 95% CI, 2.40-15.8; p<0.01), and the weakest in the group aged 31 to 40 (adjusted OR = 3.39; 95% CI, 1.73-6.63; p<0.01).

Conclusions: The prevalence of illicit drug use is high among MSM patients with HIV-1 infection in Japan. Effective intervention for illicit drug use in this population is warranted.

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Conflict of interest statement

Competing Interests: The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Patient enrollment.
See this image and copyright information in PMC

References

    1. Lehman JS, Allen DM, Green TA, Onorato IM (1994) HIV infection among non-injecting drug users entering drug treatment, United States, 1989–1992. Field Services Branch. AIDS 8: 1465–1469. - PubMed
    1. Hahn RA, Onorato IM, Jones TS, Dougherty J (1989) Prevalence of HIV infection among intravenous drug users in the United States. JAMA 261: 2677–2684. - PubMed
    1. Magnani R, Sabin K, Saidel T, Heckathorn D (2005) Review of sampling hard-to-reach and hidden populations for HIV surveillance. AIDS 19 Suppl 2S67–72. - PubMed
    1. Wada K (2011) The history and current state of drug abuse in Japan. Ann N Y Acad Sci 1216: 62–72. - PubMed
    1. Tominaga M, Kawakami N, Ono Y, Nakane Y, Nakamura Y, et al. (2009) Prevalence and correlates of illicit and non-medical use of psychotropic drugs in Japan: findings from the World Mental Health Japan Survey 2002–2004. Soc Psychiatry Psychiatr Epidemiol 44: 777–783. - PubMed

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