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. 2014 Mar-Apr;38(2):154-9.
doi: 10.1016/j.clinimag.2013.10.006. Epub 2013 Nov 7.

The usefulness of the sum of relative enhancement ratio in making a differential diagnosis of hepatocellular carcinoma from cirrhosis-related nodules

Ki Woong Yoon  1 , Ji Soo Song  2 , Young Min Han  3
Affiliations

The usefulness of the sum of relative enhancement ratio in making a differential diagnosis of hepatocellular carcinoma from cirrhosis-related nodules

Ki Woong Yoon et al. Clin Imaging. 2014 Mar-Apr.

Abstract

Objective: To estimate the diagnostic accuracy of the sum of relative enhancement ratio (sRER) in making a differential diagnosis of hepatocellular carcinoma (HCC) from benign cirrhosis-related nodules.

Materials and methods: Eighteen benign cirrhosis-related nodules and 18 HCCs were evaluated. Three radiologists independently reviewed computed tomography images using visual assessment and sRER. sRER was estimated by adding region-of-interest measurement in the arterial phase and the delayed phase. Diagnostic performance and accuracy were evaluated.

Results: The mean values of sRER were significantly higher in HCCs than in benign cirrhosis-related nodules.

Conclusion: The sRER method improved diagnostic accuracy of differentiating HCCs from benign cirrhosis-related nodules.

Keywords: Computed tomography; Hepatocellular carcinoma; Hepatocellular nodule.

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