Haematological cancer: Ikaros--not a myth for myeloma

Comment

Alessia Errico. Nat Rev Clin Oncol. 2014 Feb.

. 2014 Feb;11(2):65.

doi: 10.1038/nrclinonc.2013.237. Epub 2013 Dec 17.

No abstract available

Comment on

The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins.
Lu G, Middleton RE, Sun H, Naniong M, Ott CJ, Mitsiades CS, Wong KK, Bradner JE, Kaelin WG Jr. Lu G, et al. Science. 2014 Jan 17;343(6168):305-9. doi: 10.1126/science.1244917. Epub 2013 Nov 29. Science. 2014. PMID: 24292623 Free PMC article.
Lenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cells.
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