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Case Reports
. 2013 Jul;23(3):243-6.
doi: 10.4103/0971-3026.120283.

Herlyn-Werner-Wunderlich syndrome presenting with infertility: Role of MRI in diagnosis

Zohra Ahmad  1 , Ankur Goyal  1 , Chandan J Das  1 , Dipika Deka  2 , Raju Sharma  1
Affiliations
Case Reports

Herlyn-Werner-Wunderlich syndrome presenting with infertility: Role of MRI in diagnosis

Zohra Ahmad et al. Indian J Radiol Imaging. 2013 Jul.

Abstract

Herlyn-Werner-Wunderlich syndrome (HWWS), characterized by uterus didelphys, obstructed hemivagina, and ipsilateral renal agenesis, is an uncommon combined Mullerian and mesonephric duct anomaly, and its presentation in adulthood is even rarer. We report here a 22-year-old female presenting with primary infertility where magnetic resonance imaging (MRI) suggested the diagnosis of HWWS with endometriosis. In a patient of infertility with endometriosis and unilateral renal agenesis, diagnosis of HWWS should be suspected and MRI is the investigation of choice for such anomalies.

Keywords: Endometriosis; Herlyn-Werner-Wunderlich syndrome; infertility; magnetic resonance imaging; mullerian anomaly.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Axial T2W MRI shows two separate uterine cavities (black arrows) with two separate cervices and dilatation of left hemivagina (arrowhead)
Figure 2
Figure 2
Axial fat-suppressed T1W MRI shows hyperintense contents of dilated left hemivagina (arrow) and uterine cavity, suggestive of blood products
Figure 3
Figure 3
Sagittal T2W MRI shows right uterine cavity with normal cervix and vagina (black arrow)
Figure 4
Figure 4
Sagittal T2W MRI shows left uterine cavity (thin arrow) with dilated hemivagina (thick arrow) showing hypointense signal within a background of hyperintensity (T2 shading), suggestive of blood products within (hematometra)
Figure 5
Figure 5
Coronal T2W MRI shows multiloculated cystic lesion in left adnexa with T2 shading suggestive of blood products with endometriotic cysts
Figure 6
Figure 6
Coronal contrast-enhanced CT image reveals absent left kidney
Figure 7
Figure 7
Axial fat-supressed T1W MRI shows multilocular T1 hyperintense fluid collections in right paracolic gutter (arrow) consistent with peritoneal endometriosis
See this image and copyright information in PMC

References

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