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. 1987 Feb;7(2):946-50.
doi: 10.1128/mcb.7.2.946-950.1987.

Polyomavirus middle T antigen downregulates junctional cell-to-cell communication

R Azarnia, W R Loewenstein

Polyomavirus middle T antigen downregulates junctional cell-to-cell communication

R Azarnia et al. Mol Cell Biol. 1987 Feb.

Abstract

We examined the effect of polyomavirus middle T antigen on cell-to-cell communication in rat F cells transfected with an inducible middle T recombinant DNA or infected with a conditional mutant virus. Junctional permeability fell (reversibly) when middle T transcription was induced or when middle T was switched to the transformation+ form. The effect correlates with the rise of protein tyrosine kinase activity.

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References

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