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. 2013 Jun;15(6):467-72.
doi: 10.5812/ircmj.3370. Epub 2013 Jun 5.

Clinical lipid control success rate before and after percutaneous coronary intervention in iran; a single center study

Seyed Kianoosh Hosseini  1 , Maryam Tahvildari  2 , Mohammad Javad Alemzadeh Ansari  1 , Manouchehr Nakhjavani  3 , Alireza Esteghamati  3 , Masoumeh Lotfi Tokaldany  4
Affiliations

Clinical lipid control success rate before and after percutaneous coronary intervention in iran; a single center study

Seyed Kianoosh Hosseini et al. Iran Red Crescent Med J. 2013 Jun.

Abstract

Background: High cholesterol levels have long been considered an independent risk factor for cardiovascular disease (CVD).

Objective: Controlling risk factors such as dyslipidemia in patients with coronary artery disease is necessary. We aimed to evaluate the success rate of lipid control, during 9 months follow-up after percutaneous coronary intervention (PCI).

Patients and methods: A total of 195 patients (67.7% men, mean age = 57.8 ± 9.4 years) who underwent PCI in Tehran Heart Center were included. Serum lipid profiles were measured in all the patients before PCI and at 9-month follow-up. Dyslipidemia was defined as serum levels of LDL-C ≥ 100 or TG ≥ 150 or TC ≥ 200 or HDL-C ≤ 40 mg/dl in the men and ≤ 50 mg/dl or less in the women, or non-HDL-C ≥ 130 mg/dl with or without the consumption of lipid-lowering agents. During follow up, all patients were given atorvastatin 20-40 mg/day.

Results: Overall, 26.2% had diabetes mellitus, 42.6% had hypertension, and 34.9% were smokers. Dyslipidemia was more common in the women. At 9-month follow-up, there was no significant changes in terms of the prevalence of high HDL-C or low TG in patients; however, a significant increase was seen in the prevalence low TC in patients (63.6% vs. 80.5%; p value < 0.001), LDL-C (47.2% vs. 65.6%; p value < 0.001), and non-HDL-C (40.0% vs. 63.1%; p value < 0.001).

Conclusions: Although by current treatments, the prevalence of patients with low TC, LDL-C and non-HDL-C has significantly increased; dyslipidemia persisted in a considerable proportion of patients. These results necessitate further investigations into the relationship between high serum lipids and long-term outcome of patients after PCI as well as further evaluations of the dyslipidemia treatment strategies.

Keywords: Dyslipidemia; Lipid Control; Percutaneous Coronary Intervention.

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Figures

Figure 1.
Figure 1.. Comparison Between men and Women in Terms of the Prevalence of Dyslipidemia
Figure 2.
Figure 2.. Serum Concentration of Lipids, Before and After PCI
See this image and copyright information in PMC

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References

    1. Chrysant SG. Stopping the cardiovascular disease continuum: Focus on prevention. World J Cardiol. 2010;2(3):43–9. doi: 10.4330/wjc.v2.i3.43. - DOI - PMC - PubMed
    1. Arsenault BJ, Rana JS, Stroes ES, Despres JP, Shah PK, Kastelein JJ, et al. Beyond low-density lipoprotein cholesterol: respective contributions of non-high-density lipoprotein cholesterol levels, triglycerides, and the total cholesterol/high-density lipoprotein cholesterol ratio to coronary heart disease risk in apparently healthy men and women. J Am Coll Cardiol. 2009;55(1):35–41. doi: 10.1016/j.jacc.2009.07.057. - DOI - PubMed
    1. Eyre H, Kahn R, Robertson RM, Clark NG, Doyle C, Hong Y, et al. Preventing cancer, cardiovascular disease, and diabetes: a common agenda for the American Cancer Society, the American Diabetes Association, and the American Heart Association. Circulation. 2004;109(25):3244–55. doi: 10.1161/01.CIR.0000133321.00456.00. - DOI - PubMed
    1. Grundy SM. Obesity, metabolic syndrome, and cardiovascular disease. J Clin Endocrinol Metab. 2004;89(6):2595–600. doi: 10.1210/jc.2004-0372. - DOI - PubMed
    1. Pres D, Gasior M, Lekston A, Gierlotka M, Hawranek M, Tajstra M, et al. Relationship between low-density lipoprotein cholesterol level on admission and in-hospital mortality in patients with ST-segment elevation myocardial infarction, with or without diabetes, treated with percutaneous coronary intervention. Kardiol Pol. 2010;68(9):1005–12. - PubMed

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