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. 2013:2013:823842.
doi: 10.1155/2013/823842. Epub 2013 Nov 18.

Atypical B12 deficiency with nonresolving paraesthesia

S Haider  1 , N Ahmad  1 , E J Anaissie  2 , N Abdel Karim  2
Affiliations

Atypical B12 deficiency with nonresolving paraesthesia

S Haider et al. Case Rep Oncol Med. 2013.

Abstract

Vitamin B12 deficiency can present with various hematological, gastrointestinal and neurological manifestations. We report a case of elderly female who presented with neuropathy and vitamin B12 deficiency where the final work-up revealed polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS). This case suggests that, although POEMS syndrome is a rare entity, it can present with vitamin-B12 deficiency and thus specific work up for early diagnosis of POEMS should be considered in patients with B12 deficiency unresponsive to therapy.

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