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Review
. 2013 Aug 6:1:25.
doi: 10.3389/fpubh.2013.00025.

The utility of intravenous acetaminophen in the perioperative period

Affiliations
Review

The utility of intravenous acetaminophen in the perioperative period

Jason B O'Neal. Front Public Health. .

Abstract

Intravenous acetaminophen (IVA) has rapid and effective analgesic properties. Recent studies have shown several benefits of using IVA perioperatively. However, due to its relatively high cost and limited clinical data concerning its efficacy compared with other agents, physicians are hesitant to use IVA in the perioperative period. This brief review examines the utility of this medication in the perioperative period and highlights future areas of clinical and epidemiological research regarding its use.

Keywords: acetaminophen; intravenous; postoperative; surgery.

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References

    1. Candiotti KA, Bergese SD, Viscusi ER, Singla SK, Royal MA, Singla NK. Safety of multiple-dose intravenous acetaminophen in adult inpatients. Pain Med (2010) 11:1841–810.1111/j.1526-4637.2010.00991.x - DOI - PubMed
    1. Pergolizzi JV, Jr, Raffa RB, Tallarida R, Taylor R, Labhsetwar SA. Continuous multimechanistic postoperative analgesia: a rationale for transitioning from intravenous acetaminophen and opioids to oral formulations. Pain Pract (2012) 12:159–7310.1111/j.1533-2500.2011.00476.x - DOI - PubMed
    1. Smith HS. Perioperative intravenous acetaminophen and NSAIDs. Pain Med (2011) 12:961–8110.1111/j.1526-4637.2011.01141.x - DOI - PubMed
    1. Memis D, Inal MT, Kavalci G, Sezer A, Sut N. Intravenous paracetamol reduced the use of opioids, extubation time, and opioid-related adverse effects after major surgery in intensive care unit. J Crit Care (2010) 25:458–6210.1016/j.jcrc.2009.12.012 - DOI - PubMed
    1. Sinatra RS, Jahr JS, Reynolds L, Groudine SB, Royal MA, Breitmeyer JB, et al. Intravenous acetaminophen for pain after major orthopedic surgery: an expanded analysis. Pain Pract (2012) 12:357–6510.1111/j.1533-2500.2011.00514.x - DOI - PubMed

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