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. 2013 Dec 13;10(12):7180-92.
doi: 10.3390/ijerph10127180.

Integrated human surveillance systems of West Nile virus infections in Italy: the 2012 experience

Christian Napoli, Antonino Bella, Silvia Declich, Giuliano Grazzini, Letizia Lombardini, Alessandro Nanni Costa, Loredana Nicoletti, Maria Grazia Pompa, Simonetta Pupella, Francesca Russo, Caterina Rizzo  1
Affiliations

Integrated human surveillance systems of West Nile virus infections in Italy: the 2012 experience

Christian Napoli et al. Int J Environ Res Public Health. .

Abstract

In Italy, a West Nile virus (WNV) surveillance plan was firstly implemented in 2008 and 2009 in two affected regions and, since 2010, according to a national plan, a WNV neuroinvasive disease (WNND) surveillance has to be carried out each year during the period 15 June-30 November, in those regions where WNV circulation has been demonstrated among humans, animals or vectors. Moreover, since WNV can be transmitted to humans even by blood transfusions and organ transplants obtained from infected donors, the national surveillance integrates the blood transfusions and organs transplant surveillances too. The paper describes the results of this integrated human surveillance in Italy in 2012. Overall, in 2012, 28 autochthonous confirmed cases of WNND were reported, 14 blood donations were found WNV positive by Nucleic Acid Amplification Test and no solid organ donors tested positive for WNV. Moreover, 17 cases of WNV fever were confirmed in Veneto region. When comparing the number of WNND cases reported to the surveillance system in previous 4 years (43 cases during the period 2008-2011), with those reported in 2012 an important increase was observed in 2012. The geographic distribution of human cases was consistent with the WNV circulation among animals and vectors. Moreover, the implementation of preventive measures for WNV transmission through blood components allowed the detection of blood donors positive for WNV, avoiding the further spread of the disease. Since surveillance strategies and preventive measures are based on the integration among human, animal and vector control activities, the Italian experience could be considered a good example of collaboration among different sectors of public health in a "one health" perspective.

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Figures

Figure 1
Figure 1
WNND confirmed cases by date of symptoms onset, Italy 2008–2012.
Figure 2
Figure 2
Provinces with confirmed human cases of WNND, Italy 2012 (7 provinces, 28 cases).
Figure 3
Figure 3
WNND confirmed cases by date of symptoms onset, Italy 2012.
See this image and copyright information in PMC

References

    1. Rossini G., Cavrini F., Pierro A., Macini P., Finarelli A., Po C., Peroni G., di Caro A., Capobianchi M., Nicoletti L., et al. First human case of West Nile virus neuroinvasive infection in Italy, September 2008—Case report. Euro Surveill. 2008;13:19002. - PubMed
    1. Rizzo C., Vescio F., Declich S., Finarelli A.C., Macini P., Mattivi A., Rossini G., Piovesan C., Barzon L., Palù G., et al. West Nile virus transmission with human cases in Italy, August–September 2009. Euro Surveill. 2009;14:19353. - PubMed
    1. Rizzo C., Salcuni P., Nicoletti L., Ciufolini M.G., Russo F., Masala R., Frongia O., Finarelli A.C., Gramegna M., Gallo L., et al. Epidemiological surveillance of West Nile neuroinvasive diseases in Italy, 2008 to 2011. Euro Surveill. 2012;17:20172. - PubMed
    1. Sorveglianza della malattia di West Nile in Italia, 2010. [(accessed on 27 September 2013)]. (in Italian) Available online: http://www.normativasanitaria.it/normsan-pdf/0000/34923_1.pdf.
    1. Sorveglianza dei casi umani delle malattie trasmesse da vettori con particolare riferimento alla chikungunya, dengue e West Nile disease—2011. [(accessed on 27 September 2013)]. (in Italian) Available online: http://www.normativasanitaria.it/normsan-pdf/0000/39170_1.pdf.

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