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. 2014 Jul;25(8):593-5.
doi: 10.1177/0956462413515636. Epub 2013 Dec 18.

Clinical and epidemiological characteristics of individuals with very high rapid plasma reagin

Jose G Castro  1 , Maria L Alcaide  2 , Isabella Rosa-Cunha  2
Affiliations

Clinical and epidemiological characteristics of individuals with very high rapid plasma reagin

Jose G Castro et al. Int J STD AIDS. 2014 Jul.

Abstract

The objective of the study was to identify clinical and epidemiological characteristics of patients with infectious syphilis who presented with a high rapid plasma reagin (RPR) titre (≥1: 512) during the year of 2009 at the Miami Dade County Health Department (MDCHD) STD clinic. Potential cases were identified by a search in the electronic database. Among 519 individuals identified with reactive RPR, 190 individuals met criteria for infectious syphilis and 32 of them had at least one RPR titre of ≥1: 512. We found that the majority of individuals with high RPR were men who have sex with men (82%), from ethnic minorities (91%), and HIV infected (75%) but only 3 of them were on antiretroviral therapy. Overall, 50% of these patients with very high RPR titres were symptomatic, and the most common symptom was skin rash (93%).

Keywords: AIDS; HIV; MSM; Syphilis; Treponema pallidum; high RPR; rapid plasma reagin; sexually transmitted infection.

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