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. 2013 Jan;29(1):15-20.
doi: 10.12669/pjms.291.2896.

Frequency of Vitamin D deficiency in pregnant diabetics at Baskent University Hospital, Istanbul

Hulya Parildar  1 , Asli Dogruk Unal  2 , Guldeniz Aksan Desteli  3 , Ozlem Cigerli  4 , Nilgun Guvener Demirag  5
Affiliations

Frequency of Vitamin D deficiency in pregnant diabetics at Baskent University Hospital, Istanbul

Hulya Parildar et al. Pak J Med Sci. 2013 Jan.

Abstract

Objective: To find out the frequency of vitamin D deficiency and its relation with glucose parameters and the incidence of gestational diabetes (GDM).

Methodology: Gestational diabetes was diagnosed with 75 gram oral glucose tolerance test. Forty-four pregnant women diagnosed with GDM and 78 non-GDM pregnant women were enrolled as case and control group, respectively in this descriptive study. Vitamin D status was classified as deficiency at ≤20 ng/ml for serum 25(OH)D concentrations.

Results: The mean ages were 33.4±5.2 (18-44) years and 29.7±4.1 (21-39) years, mean BMI was 30.6±5.9 kg/m² (19.5-46.1) and 25.9±4.4 kg/m2 (16.5-38) in case and control groups, respectively. The frequency of GDM was found 9.38%. The mean serum vitamin D levels in GDM group were significantly lower than in non-GDM subjects (p=0.07). A total of 56.8% of GDM patients were compared with 35.8% of control group which had Vitamin D deficiency and the difference was significant (p= 0.02). There was no significant association between vitamin D levels and fasting glucose, insulin and HbA1c. Vitamin D levels were inversely correlated with clothing style, parathyroid hormone levels, dental problems and muscle cramps.

Conclusions: The association of maternal Vitamin D status with the markers of glucose metabolism in pregnancy needs prospective studies.

Keywords: Gestational diabetes; Nutrition in pregnancy; Vitamin D.

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Figures

Fig.1
Fig.1
The correlation between serum Vitamin D and PTH levels
Fig.2
Fig.2
Serum Vitamin D levels in veiled and nonveiled pregnant
Fig.3
Fig.3
Vitamin D levels and the frequency of muscle cramps (x²=3.57, p=0.05).
Fig.4
Fig.4
Vitamin D levels and the frequency of dental problems (x²=4.67, p=0.03).
See this image and copyright information in PMC

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