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Case Reports
. 2013 Apr;29(2):663-5.
doi: 10.12669/pjms.292.2981.

Treatment of gestational choriocarcinoma and massive ascites by hypothermic intraperitoneal perfusion chemotherapy guided by ultrasound followed by cytoreductive surgery

Ming-Chen Ba  1 , Hui Long  1 , Yin-Bing Wu  2
Affiliations
Case Reports

Treatment of gestational choriocarcinoma and massive ascites by hypothermic intraperitoneal perfusion chemotherapy guided by ultrasound followed by cytoreductive surgery

Ming-Chen Ba et al. Pak J Med Sci. 2013 Apr.

Abstract

A 33-year-old woman with very poor health status was admitted to our hospital because she had experienced increasing abdominal distention for three months, CT examination showed a right ovarian tumor together with massive abdominal and pelvic fluid. The patient was first treated by continuous circulatory hypothermic intraperitoneal perfusion chemotherapy (HIPC) guided by B-mode ultrasound, followed by cytoreductive surgery (CRS) after her ascites was controlled and her health condition improved. She was diagnosed with gestational choriocarcinoma (GC) based on the pathological examination of the hysterectomy specimen. She is still alive with very good health today. We think it may be a good choice for a patient in very poor health with GC accompanied by massive ascites to perform HIPC guided by B-mode ultrasound firstly, followed by CRS when the ascites has relieved and the patient's health has improved.

Keywords: Chemotherapy; Gestational choriocarcinoma; Hypothermic; Intraperitoneal perfusion; Malignant ascites; Ultrasound.

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Figures

Fig.1
Fig.1
Computed tomography examination showed a right ovarian tumor with a size of 17.3 cm × 16.2 cm ×12.3 cm accompanied by significant abdominal and pelvic fluid
Fig.2
Fig.2
Chest X-rays examination showed a lot of right pleural effusion
See this image and copyright information in PMC

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References

    1. Kairi-Vassilatou E, Papakonstantinou K, Grapsa D, Kondi-Paphiti A, Hasiakos D. Primary gestational choriocarcinoma of the uterine cervix. Report of a case and review of the literature. Int J Gynecol Cancer. 2007;17(4):921–925. - PubMed
    1. Helm CW, Bristow RE, Kusamura S, Baratti D, Deraco M. Hyperthermic intraperitoneal chemotherapy with and without cytoreductive surgery for epithelial ovarian cancer. J Surg Oncol. 2008;98(4):283–290. - PubMed
    1. Ba MC, Cui SZ, Lin SQ, Tang YQ, Wu YB, Wang B, et al. Chemotherapy with laparoscope-assisted continuous circulatory hyperthermic intraperitoneal perfusion for malignant ascites. World J Gastroenterol. 2010;16(15):1901–1907. - PMC - PubMed
    1. Nguyen PT, Chang KJ. EUS in the detection of ascites and EUS-guided paracentesis. Gastrointest Endosc. 2001;54(3):336–339. - PubMed
    1. Cui S, Ba M, Tang Y, Liu J, Wu Y, Wang B, et al. B ultrasound-guided hyperthermic intraperitoneal perfusion chemotherapy for the treatment of malignant ascites. Oncol Rep. 2012;28(4):1325–1331. - PubMed

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