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Review
. 2013 May;29(3):891-6.
doi: 10.12669/pjms.293.3497.

Platelet receptors; an instrumental of platelet physiology

Muhammad Saboor  1 , Qamar Ayub  2 , Samina Ilyas  3 , Moinuddin  4
Affiliations
Review

Platelet receptors; an instrumental of platelet physiology

Muhammad Saboor et al. Pak J Med Sci. 2013 May.

Abstract

Platelets play an important role in hemostasis, inflammation, host defense, tumor growth and metastasis. Platelets receptors are instrumental in platelet-platelet aggregation and interaction of platelets with leukocytes, endothelial cells and coagulation factors. These receptors are also the targets for antiplatelet drugs. This review focuses on the role of platelet receptors in human physiology. Data were extracted from peer-reviewed journals using MEDLINE and EMBASE databases, and the following terms (platelets, platelet receptors, CD markers, integrins, tetraspanins, transmembrane receptors, prostaglandin receptors, immunoglobulin superfamily receptors) were used.

Keywords: Integrins; Platelet receptors; Selectins; Tetraspanins.

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