Outcome of conventional IVF and ICSI on sibling oocytes in moderate ligoasthenozoospermia
- PMID: 24353724
- PMCID: PMC3858934
Outcome of conventional IVF and ICSI on sibling oocytes in moderate ligoasthenozoospermia
Abstract
Objective: To evaluate the outcomes of patients with moderate oligoasthenozoospermia treated with conventional in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI).
Methods: A total of 99 couples with moderate oligoasthenozoospermia undergoing their first IVF/ICSI cycle were included in the study. Sibling oocytes were randomized to be inseminated either by conventional IVF or ICSI. Fertilization rate, cleavage rate, embryo quality, implantation rate, and clinical pregnancy rate were examined.
Results: There was no difference in the fertilization rate, cleavage rate, implantation rate, and pregnancy rate between conventional IVF and ICSI (P>0.05). The good quality embryo rate was significant difference between after IVF and after ICSI (P<0.05).
Conclusions: Couples with moderate oligoasthenozoospermia did not influence the major indices of IVF and the uncertainties concerning the safety of ICSI, couples with moderate oligoasthenozoospermia need not be subjected to ICSI.
Keywords: In vitro fertilization (IVF); Infertility; Intracytoplasmic sperm injection (ICSI); Oligoasthenozoospermia.
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References
-
- World Health Organization. WHO laboratory manual for the examination and processing of human semen. 5th ed. Cambridge University Press; 2010.
-
- Plachot M, Belaisch-Allart J, Mayenga JM, Chouraqui A, Tesquier L, Serkine AM. Outcome of conventional IVF and ICSI on sibling oocytes in mild male factor infertility. Hum Reprod. 2002;17(2):362–369. - PubMed
-
- Van Der Westerlaken L, Naaktgeboren N, Verburg H, Dieben S, Helmerhorst FM. Conventional in vitro fertilization versus intracytoplasmic sperm injection in patients with borderline semen: a randomized study using sibling oocytes. Fertil Steril. 2006;85:395–400. - PubMed
-
- Nagy ZP, Verheyen G, Tournaye H, Van Steirteghem AC. Special applications of intracytoplasmic sperm injection: the influence of sperm count, motility, morphology, source and sperm antibody on the outcome of ICSI. Hum Reprod. 1998;Suppl:143–154. - PubMed
-
- Sarkar NN. Intracytoplasmic sperm injection: an assisted reproductive technique and its outcome to overcome infertility. J Obstet Gynaecol. 2007;27:347–353. - PubMed
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