Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2013 Dec;26(6):636-8.
doi: 10.1177/197140091302600605. Epub 2013 Dec 18.

Subdural B cell lymphoma. Imaging features, histopathology. Literature review

Naga Varaprasad Vemuri  1 , Lakshmi Sudha Prasanna Karanam, L Rambabu, V S N Rao, K Kalyan, G Sateesh
Affiliations
Review

Subdural B cell lymphoma. Imaging features, histopathology. Literature review

Naga Varaprasad Vemuri et al. Neuroradiol J. 2013 Dec.

Abstract

Dural-based B cell lymphomas are rare and have a female preponderance. A 60-year-old Asian man with a history of trivial trauma presented with generalised tonic clonic seizures and headache. Imaging and clinical work-up was done. A temporoparietal subdural lesion with no evidence of systemic lymphoma was detected. Intraoperatively, a dural-based mass lesion was seen with thickened dura and biopsy-proven B cell lymphoma, and the patient was then kept on chemotherapy. A suspicion of this rare entity should be considered in imaging of dural-based lesions.

Keywords: MRI; dural lymphoma.

PubMed Disclaimer

Figures

Figure 1
Figure 1
A,B) Brain computed tomography showing a hyperdense lesion in the right temporoparietal region with surrounding oedema and mass effect. C) Bone window shows no erosions with normal cranial vault.
Figure 2
Figure 2
A) MR imaging showing a hypointense subdural lesion in the right temporoparietal region on a T1-weighted sequence. B,C) A hypointense signal intense subdural lesion with surrounding oedema causing midline shift of 11 mm to the left on gradient echo venous bold sequence.
Figure 3
Figure 3
A) Intraoperative photograph showing the dural-based tumour. B) Histological examination photomicrograph showing diffuse lymphoid cell infiltrate. C) Immunohistochemistry showing cytoplasmic positivity with CD19 and CD20 markers.
See this image and copyright information in PMC

References

    1. Bellinzona M, Roser F, Ostertag H, et al. Surgical removal of primary central nervous system lymphomas (PCNSL) presenting as space occupying lesions: a series of 33 cases. Eur J Surg Oncol. 2005;31(1):100–105. - PubMed
    1. Mead GM, Bleehen NM, Gregor A, et al. A medical research council randomized trial in patients with primary cerebral non-Hodgkin lymphoma: cerebral radiotherapy with and without cyclophosphamide, doxorubicin, vincristine, and prednisone chemotherapy. Cancer. 2000;89(6):1359–1370. - PubMed
    1. Benouaich A, Delord JP, Danjou M, et al. Primary dural lymphoma: a report of two cases with review of the literature. Rev Neurol (Paris) 2003;159(6-7 Pt 1):652–658. - PubMed
    1. Iwamoto FM, DeAngelis LM, Abrey LE. Primary dural lymphomas: a clinicopathologic study of treatment and outcome in eight patients. Neurology. 2006;66:1763–1765. - PubMed
    1. Galarza M, Gazzeri R, Elfeky HA, et al. Primary diffuse large B-cell lymphoma of the dura mater and cranial vault. Case report and literature review. Neurosurg Focus. 2006;21(5):E10. - PubMed

LinkOut - more resources