Subdural B cell lymphoma. Imaging features, histopathology. Literature review

Abstract

Dural-based B cell lymphomas are rare and have a female preponderance. A 60-year-old Asian man with a history of trivial trauma presented with generalised tonic clonic seizures and headache. Imaging and clinical work-up was done. A temporoparietal subdural lesion with no evidence of systemic lymphoma was detected. Intraoperatively, a dural-based mass lesion was seen with thickened dura and biopsy-proven B cell lymphoma, and the patient was then kept on chemotherapy. A suspicion of this rare entity should be considered in imaging of dural-based lesions.

Keywords: MRI; dural lymphoma.

Figure 1

A,B) Brain computed tomography showing a hyperdense lesion in the right temporoparietal region with surrounding oedema and mass effect. C) Bone window shows no erosions with normal cranial vault.

Figure 2

A) MR imaging showing a hypointense subdural lesion in the right temporoparietal region on a T1-weighted sequence. B,C) A hypointense signal intense subdural lesion with surrounding oedema causing midline shift of 11 mm to the left on gradient echo venous bold sequence.

Figure 3

A) Intraoperative photograph showing the dural-based tumour. B) Histological examination photomicrograph showing diffuse lymphoid cell infiltrate. C) Immunohistochemistry showing cytoplasmic positivity with CD19 and CD20 markers.