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Comment
. 2014 Jan 7;33(1):5-6.
doi: 10.1002/embj.201387363. Epub 2013 Dec 19.

Lin28a--boost your energy for youthful regeneration

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Comment

Lin28a--boost your energy for youthful regeneration

Martin D Burkhalter et al. EMBO J. .

Abstract

The regenerative capacity of most tissues declines dramatically after embryonic development and during post-natal life. The underlying mechanisms of this phenomenon are incompletely understood. In a recent issue of Cell, Shyh-Chang and colleagues provide experimental evidence that Lin28 prolongs youthful regenerative capacity by increasing oxidative glucose metabolism (Shyh-Chang et al, 2013).

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