Three-dimensional structure of a complex of antibody with influenza virus neuraminidase
- PMID: 2436051
- DOI: 10.1038/326358a0
Three-dimensional structure of a complex of antibody with influenza virus neuraminidase
Abstract
The structure of a complex between influenza virus neuraminidase and an antibody displays features inconsistent with the inflexible 'lock and key' model of antigen-antibody binding. The structure of the antigen changes on binding, and that of the antibody may also change; the interaction therefore has some of the character of a handshake.
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