A new roadmap for drug development for Alzheimer's disease
- PMID: 24362362
- PMCID: PMC4668586
- DOI: 10.1038/nrd3842-c2
A new roadmap for drug development for Alzheimer's disease
Comment on
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Sting of Alzheimer's failures offset by upcoming prevention trials.Nat Rev Drug Discov. 2012 Sep;11(9):657-60. doi: 10.1038/nrd3842. Nat Rev Drug Discov. 2012. PMID: 22935790 No abstract available.
References
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- Mullard A. Sting of Alzheimer’s failures offset by upcoming prevention trials. Nature Rev. Drug Discov. 2012;11:657–660. - PubMed
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- Aisen PS, Vellas B, Hampel H. Moving towards early clinical trials for amyloid-targeted therapy in Alzheimer’s disease. Nature Rev. Drug Discov. 2013;12:324. - PubMed
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- Buchhave P, et al. Cerebrospinal fluid levels of β-amyloid 1–42, but not of tau, are fully changed already 5 to 10 years before the onset of Alzheimer dementia. Arch. Gen. Psychiatry. 2012;69:98–106. - PubMed
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- Pike KE, et al. Cognition and β-amyloid in preclinical Alzheimer’s disease: data from the AIBL study. Neuropsychologia. 2011;49:2384–2390. - PubMed
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