Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2013 Dec 20;19(1):78-101.
doi: 10.3390/molecules19010078.

Structure and antioxidant activity of polyphenols derived from propolis

Anna Kurek-Górecka  1 , Anna Rzepecka-Stojko, Michał Górecki, Jerzy Stojko, Marian Sosada, Grażyna Swierczek-Zieba
Affiliations
Review

Structure and antioxidant activity of polyphenols derived from propolis

Anna Kurek-Górecka et al. Molecules. .

Abstract

Propolis is a potential source of natural antioxidants such as phenolic acids and flavonoids. Its wide biological effects have been known and used since antiquity. In the modern world natural substances are sought which would be able to counteract the effects of antioxidative stress, which underlies many diseases, such as cancer, diabetes and atherosclerosis. This paper aims to present the antioxidative activity of phenolic acids and flavonoids present in Polish propolis and the relationship between their chemical structure and antioxidative activity influencing its medicinal properties. Data concerning the biological activity of propolis are summarized here, including its antibacterial, anti-inflammatory, anticarcinogenic, antiatherogenic, estrogenic effects, as well as AIDS- counteracting and reparative-regenerative function.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Oxidation of phenolic compounds [25].
Figure 2
Figure 2
Basic flavonoid structure [39].
Figure 3
Figure 3
Metal-binding sites for flavonoids [26].
See this image and copyright information in PMC

References

    1. Kędzia B. Chemical composition of polish propolis. Part I. The initial period of investigations. Post. Fitoter. 2009;1:39–44.
    1. Kędzia B. Chemical composition of polish propolis. Part II. New Studies. Post. Fitoter. 2009;2:122–128.
    1. Olczyk P., Komosińska-Vassev K., Olczyk K. Propolis-chemical composition, properties and application. Farm. Pol. 2007;63:1102–1107.
    1. Kędzia B., Hołderna-Kędzia E. Chemical composition of propolis in nowadays researches. Herba Pol. 1991;38:95–107.
    1. Khalil M.L. Biological activity of bee propolis in health and disease. Asian Pac. J. Cancer Prev. 2006;7:22–31. - PubMed

Publication types

MeSH terms