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. 2014 Mar;58(6):830-3.
doi: 10.1093/cid/cit934. Epub 2013 Dec 20.

The pertussis problem

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The pertussis problem

Stanley A Plotkin. Clin Infect Dis. 2014 Mar.

Abstract

Pertussis is resurgent, and many cases are occurring in vaccinated children and adolescents. In countries using acellular vaccines, waning immunity is at least part of the problem. This article discusses possible improvements in those vaccines.

Keywords: Th1 responses; adjuvants; pertussis; pertussis toxin; waning immunity.

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