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. 2013:2013:210490.
doi: 10.1155/2013/210490. Epub 2013 Dec 2.

Epidemiology of human respiratory viruses in children with acute respiratory tract infections in Jinan, China

Yanqin Lu  1 , Shifu Wang  2 , Lehai Zhang  2 , Chao Xu  1 , Cuirong Bian  3 , Zhaoxia Wang  4 , Yanhui Ma  5 , Ke Wang  1 , Lixia Ma  5 , Chen Meng  5 , Caiyun Ni  5 , Jiabei Tong  1 , Gongchao Li  1 , Jinxiang Han  1
Affiliations

Epidemiology of human respiratory viruses in children with acute respiratory tract infections in Jinan, China

Yanqin Lu et al. Clin Dev Immunol. 2013.

Abstract

The viral etiologies of UTRIs and LTRIs in children in Jinan city were investigated between July 2009 and June 2010. Nasal and throat swabs were collected from 397 children with URTIs and bronchoalveolar lavage fluid specimens were collected from 323 children with LRTIs. RT-PCR/PCR was used to examine all samples for IFV, PIV, RSV, RV, hMPV, HBoV, CoV, ADV, RSV, and EV. Viral pathogens were detected in 47.10% of URTI samples and 66.57% samples, and the incidence of viral coinfection was 5.29% and 21.05%, respectively. IFV was the most common virus in URTIs, with a detection rate of 19.40%, followed by PIV (10.83%), RV (10.58%), and EV (6.30%). For LRTIs, PIV and RV were both detected in 27% of samples, followed by RSV (9.91%), HBoV (8.36%), IFV (5.57%), and hMPV (5.57%). RSV and HBoV were more prevalent in the youngest children of no more than six months. Meanwhile, RV, PIV, and RSV were the most frequent viruses combined with bacterial pathogens in LRTIs. In conclusion, the spectrum of respiratory virus infections in URTIs and LRTIs differed in terms of the most common pathogens, seasonal distribution, and coinfection rate.

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Figures

Figure 1
Figure 1
Number of recruited patients and the numbers of positive samples for viral infections.
Figure 2
Figure 2
Number of positive results for various viruses in patients with acute upper respiratory tract infections.
Figure 3
Figure 3
Number of positive results for various viruses in patients with acute lower respiratory tract infections.
Figure 4
Figure 4
Percentage of samples that was positive for various viruses in different age groups of patients.
See this image and copyright information in PMC

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