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Meta-Analysis
. 2014 Feb 4;110(3):802-7.
doi: 10.1038/bjc.2013.762. Epub 2013 Dec 24.

Statin use is not associated with reduced risk of skin cancer: a meta-analysis

X Li  1 , X B Wu  1 , Q Chen  1
Affiliations
Meta-Analysis

Statin use is not associated with reduced risk of skin cancer: a meta-analysis

X Li et al. Br J Cancer. .

Abstract

Background: There is contradictory evidence about the association between statin and skin cancer.

Methods: Literature search in PubMed and Web of Science was undertaken up to June 2013. Pooled relative risk (RR) estimates and 95% confidence intervals (CIs) were calculated.

Result: A total of 21 articles with 29 studies were identified. No association was found between statin and skin cancer among neither melanoma (RR, 0.94; 95% CI, 0.85-1.04) nor non-melanoma skin cancer (RR, 1.03; 95% CI, 0.90-1.19).

Conclusion: Our meta-analysis does not support a potential role of statin use in the prevention of skin cancer.

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