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Review
. 2013 Dec;25(4):155-64.
doi: 10.5792/ksrr.2013.25.4.155. Epub 2013 Nov 29.

Periprosthetic knee infection: ten strategies that work

Javad Parvizi  1 , Priscilla Ku Cavanaugh  1 , Claudio Diaz-Ledezma  1
Affiliations
Review

Periprosthetic knee infection: ten strategies that work

Javad Parvizi et al. Knee Surg Relat Res. 2013 Dec.

Abstract

Periprosthetic joint infection (PJI) is one of the most serious complications following total knee arthroplasty (TKA). The demand for TKA is rapidly increasing, resulting in a subsequent increase in infections involving knee prosthesis. Despite the existence of common management practices, the best approach for several aspects in the management of periprosthetic knee infection remains controversial. This review examines the current understanding in the management of the following aspects of PJI: preoperative risk stratification, preoperative antibiotics, preoperative skin preparation, outpatient diagnosis, assessing for infection in revision cases, improving culture utility, irrigation and debridement, one and two-stage revision, and patient prognostic information. Moreover, ten strategies for the management of periprosthetic knee infection based on available literature, and experience of the authors were reviewed.

Keywords: Arthroplasty; Infection control; Knee; Periprosthetic joint infection; Reoperation.

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Conflict of interest statement

Javad Parvizi: Speakers bureau/paid presentations: Elsevier, Wolters Kluwer, Slack, Datarace; Consulting: Zimmer, Smith& Nephew, Convatech, TissueGene, Ceramtec, Emovi, 3M, Cadence, Medtronic, Pfizer; Stock: SmarTech, Hip Innovation Technology; Medical/Orthoapedics publications editorials/governing board: Journal of Athroplasty, Journal of Bone and Joint Surgery, Bone and Joint Journal; Service on Committees/Boards: Philadelphia Orthopaedics, Eastern Orthopaedics, CD Diagnostics, United Healthcare, Magnifi Group (Publishers), 3M.

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References

    1. Namba RS, Inacio MC, Paxton EW. Risk factors associated with deep surgical site infections after primary total knee arthroplasty: an analysis of 56,216 knees. J Bone Joint Surg Am. 2013;95:775–782. - PubMed
    1. Workgroup of the American Association of Hip and Knee Surgeons Evidence Based Committee. Obesity and total joint arthroplasty: a literature based review. J Arthroplasty. 2013;28:714–721. - PubMed
    1. Jamsen E, Nevalainen P, Eskelinen A, Huotari K, Kalliovalkama J, Moilanen T. Obesity, diabetes, and preoperative hyperglycemia as predictors of periprosthetic joint infection: a single-center analysis of 7181 primary hip and knee replacements for osteoarthritis. J Bone Joint Surg Am. 2012;94:e101. - PubMed
    1. Iorio R, Williams KM, Marcantonio AJ, Specht LM, Tilzey JF, Healy WL. Diabetes mellitus, hemoglobin A1C, and the incidence of total joint arthroplasty infection. J Arthroplasty. 2012;27:726–729. - PubMed
    1. Berbari EF, Osmon DR, Lahr B, Eckel-Passow JE, Tsaras G, Hanssen AD, Mabry T, Steckelberg J, Thompson R. The Mayo prosthetic joint infection risk score: implication for surgical site infection reporting and risk stratification. Infect Control Hosp Epidemiol. 2012;33:774–781. - PubMed

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