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Comment
. 2014 Jan;46(1):5-6.
doi: 10.1038/ng.2859.

Genetic signature of bacterial pathogen adaptation during chronic pulmonary infections

Steve P Bernier  1 , Matthew L Workentine  1 , Michael G Surette  1
Affiliations
Comment

Genetic signature of bacterial pathogen adaptation during chronic pulmonary infections

Steve P Bernier et al. Nat Genet. 2014 Jan.

Abstract

To establish and maintain chronic infections, many pathogens adapt in response to selective pressures within the host, leaving unique genetic signatures. A new study uses whole-genome and population sequencing approaches to identify evidence of adaptive evolution in Burkholderia dolosa genomes isolated from chronic infections in patients with cystic fibrosis.

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References

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