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. 1987;86(3):225-7.
doi: 10.1007/BF00490251.

Identification of osteoclasts and their differentiation from mononuclear phagocytes by enzyme histochemistry

W Hermanns

Identification of osteoclasts and their differentiation from mononuclear phagocytes by enzyme histochemistry

W Hermanns. Histochemistry. 1987.

Abstract

A double staining method is presented which allows the enzyme histochemical differentiation between osteoclasts (mono- and multinucleated forms) and mononuclear phagocytes (macrophages, multinucleated inflammatory giant cells). Osteoclasts are characterized by a strong acid phosphatase activity whereas macrophages and inflammatory giant cells show a variable non-specific esterase activity. The described method may be useful in studying the osteoclast origin and the extraosseous distribution of these cells.

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