Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2012 Sep 19;2(4):139-42.
doi: 10.1016/j.gynor.2012.09.001. eCollection 2012.

A case of small cell carcinoma of the ovary hypercalcemic variant in a teenager

Affiliations

A case of small cell carcinoma of the ovary hypercalcemic variant in a teenager

Arvind Bakhru et al. Gynecol Oncol Case Rep. .

Abstract

► Young women with hypercalcemic type small cell ovarian cancer face a poor prognosis. ► Tumors respond to multi-agent chemotherapy, although rapid recurrence is typical. ► Using updated immunohistochemical staining patterns, this tumor can be identified.

Keywords: Chemotherapy; Histology; Hypercalcemic; Ovarian cancer; Small cell carcinoma.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Initial pelvic mass, prior to surgery.
Fig. 4
Fig. 4
Gross pathology.
Fig. 5
Fig. 5
H&E Histology. Panel A — sheets of tumor cells with fibroepithelial bands and absent stroma; areas of cystic change from necrosis, 4 ×. Panel B – follicle like spaces are noted, 20 ×. Panel C — high power view of the tumor cells, 60x. Panel D — microscopic metastasis to the omenum, 10 ×.

References

    1. Barondeau J., Rodgers M., Braun L., Azarow K., Forouhar M., Faucette K. Small cell ovarian carcinoma: a rare, aggressive tumor masquerading as constipation in a teenager with a fatal outcome. J Pediatr Hematol Oncol. 2010;32(4):e139–e141. (May). PMID: 20057325. - PubMed
    1. Blatt J., Van Le L., Weiner T., Sailer S. Ovarian carcinoma in an adolescent with transgenerational exposure to diethylstilbestrol. J Pediatr Hematol Oncol. 2003;25(8):635–636. (Aug) - PubMed
    1. Di Vagno G., Melilli G.A., Cormio G., Piscitelli D., Ciampolillo A., Resta L., Selvaggi L. Large-cell variant of small cell carcinoma of the ovary with hypercalcaemia. Arch. Gynecol. Obstet. 2000;264(3):157–158. (Nov) - PubMed
    1. Dickersin G.R., Kline I.W., Scully R.E. Small cell carcinoma of the ovary with hypercalcemia: a report of eleven cases. Cancer. 1982;49:188–197. - PubMed
    1. Harrison M.L., Hoskins P., du Bois A., Quinn M., Rustin G.J., Ledermann J.A., Baron-Hay S., Friedlander M.L. Small cell of the ovary, hypercalcemic type—analysis of combined experience and recommendation for management. A GCIG study. Gynecol. Oncol. 2006;100:233–238. - PubMed

LinkOut - more resources