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. 2012 Sep 26;1(1):88-90.
doi: 10.1016/j.mmcr.2012.09.003. eCollection 2012.

Geotrichum capitatum septicemia in patients with acute myeloid leukemia. Report of three cases

Fatma Saghrouni  1 , Jihene Ben Abdeljelil  1 , Yosra Ben Youssef  2 , Nour Ben Abdeljelil  3 , Soukeina Gheith  1 , Akila Fathallah  1 , Moncef Ben Said  1
Affiliations

Geotrichum capitatum septicemia in patients with acute myeloid leukemia. Report of three cases

Fatma Saghrouni et al. Med Mycol Case Rep. .

Abstract

Geotrichum capitatum infection is uncommon, and has been exclusively reported in immunocompromised patients. The prognosis is poor with a mortality rate ranging from 50 to 90%. We report 3 cases of Geotrichum capitatum fungemia in neutropenic patients receiving chemotherapy for acute myeloblastic leukemia. The infection was successfully cured with voriconazole in 1 case and was fatal in the 2 remaining cases despite treatment with amphotericin B.

Keywords: Acute myeloid leukemia; Fungemia; Geotrichum capitatum; Neutropenia.

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References

    1. Martino P., Venditti M., Micozzi A., Morace G., Polonelli L., Mantovani M.P. Blastoschizomyces capitatus: an emerging cause of invasive fungal disease in leukemia patients. Reviews of Infectious Diseases. 1990;12:570–582. - PubMed
    1. Shiemann R., Glasmacher A., Bailly E., Horré R., Molitor E., Leutner C. Geotrichum capitatum septicaemia in neutropenic patients: case report and review of the literature. Mycoses. 1998;41:113–116. - PubMed
    1. Fouassier M., Joly D., Cambon M., Peigue-Lafeuille H., Condat P. Geotrichum capitatum infection in a neutropenic patient, case report and review of the literature. Revue de Medecine Interne. 1998;19:431–433. - PubMed
    1. Koll B.S., Brown A.E. Changing patterns of infections in the immuno-compromised patient with cancer. Hematology–Oncology Clinics of North America. 1993;7:753–769. - PubMed
    1. Martino R., Subira M. Invasive fungal infections in hematology: new trends. Annals of Hematology. 2002;81:233–243. - PubMed

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