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Review
. 2014 Mar;109(4):352-6.
doi: 10.1002/jso.23540. Epub 2013 Dec 24.

Isolated limb infusion: technical aspects

Hidde M Kroon  1 , Annemarleen Huismans, Richard C Waugh, Peter C A Kam, John F Thompson
Affiliations
Review

Isolated limb infusion: technical aspects

Hidde M Kroon et al. J Surg Oncol. 2014 Mar.

Abstract

Objective: To describe the technique of isolated limb infusion (ILI) for regional high dose chemotherapy in patients with advanced malignancies confined to a limb, as currently practiced at Melanoma Institute Australia (MIA).

Background: ILI is progressively being used around the world but to date the reported response rates are generally lower than those reported by MIA.

Discussion: This description of the ILI protocol at MIA provides details that may allow other surgeons to improve results.

Keywords: in transit metastasis; isolated limb infusion; melanoma; soft tissue sarcoma; toxicity.

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