Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 Jan;23 Suppl 1(Suppl 1):92-101.
doi: 10.1002/mpr.1412.

Emerging clinical trends and perspectives on comorbid patterns of mental disorders in research

Giovanni A Fava  1 , Eliana Tossani, Per Bech, Carmen Berrocal, Guy Chouinard, Claudio Csillag, Hans-Ulrich Wittchen, Winfried Rief
Affiliations

Emerging clinical trends and perspectives on comorbid patterns of mental disorders in research

Giovanni A Fava et al. Int J Methods Psychiatr Res. 2014 Jan.

Abstract

Comorbidity is a well-established and documented phenomenon in mental disorders and medicine with heuristic value. The concept of comorbidity remains however poorly defined and lacks a comprehensive and coherent theoretical framework. There is a need to develop coherent methodological strategies in order to promote a fuller understanding of the implications of comorbidity and to exploit its potential value with regard to etiopathogenic and therapeutic issues. This position paper makes recommendations of improved methodological standards and procedures and discusses a range of options that can provide incremental information that is likely to improve therapeutic outcomes.

Keywords: clinical trials; comorbidity; iatrogenic disturbances; illness behaviour; mental disorder; psychological well-being.

PubMed Disclaimer

References

    1. American Psychiatric Association (APA) . (1980) Diagnostic and Statistical Manual of Mental Disorders: DSM‐III, Washington, DC, American Psychiatric Publishing.
    1. American Psychiatric Association (APA) . (2000) Diagnostic and Statistical Manual of Mental Disorders: DSM‐IV‐TR, Washington, DC, American Psychiatric Publishing.
    1. Andrews G. (1996) Comorbidity and the general neurotic syndrome. British Journal of Psychiatry, l68(Suppl. 30), 76–84. - PubMed
    1. Bech P. (2010) Struggle for subtypes in primary and secondary depression and their mode‐specific treatment or healing. Psychotherapy and Psychosomatics, 79(6), 331–338. - PubMed
    1. Bech P. (2012) Clinical psychometrics, Oxford, Wiley‐Blackwell.