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. 2014 Jan;23 Suppl 1(Suppl 1):92-101.
doi: 10.1002/mpr.1412.

Emerging clinical trends and perspectives on comorbid patterns of mental disorders in research

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Emerging clinical trends and perspectives on comorbid patterns of mental disorders in research

Giovanni A Fava et al. Int J Methods Psychiatr Res. 2014 Jan.

Abstract

Comorbidity is a well-established and documented phenomenon in mental disorders and medicine with heuristic value. The concept of comorbidity remains however poorly defined and lacks a comprehensive and coherent theoretical framework. There is a need to develop coherent methodological strategies in order to promote a fuller understanding of the implications of comorbidity and to exploit its potential value with regard to etiopathogenic and therapeutic issues. This position paper makes recommendations of improved methodological standards and procedures and discusses a range of options that can provide incremental information that is likely to improve therapeutic outcomes.

Keywords: clinical trials; comorbidity; iatrogenic disturbances; illness behaviour; mental disorder; psychological well-being.

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