Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2013 Dec;33(6):428-30.

Keratoacanthoma: an unusual nasal mass

M S Sazafi  1 , H Salina  1 , A Asma  1 , N Masir  2 , S H A Primuharsa Putra  3
Affiliations
Case Reports

Keratoacanthoma: an unusual nasal mass

M S Sazafi et al. Acta Otorhinolaryngol Ital. 2013 Dec.

Abstract
in English, Italian

We report a case of keratoacanthoma in a non-sun-exposed nasal vestibule of an 84-year-old man. He presented with a progressively growing left nasal mass that had been present for 8 months. Examination showed a non-tender protruding mass arising from medial vestibular wall of the left nostril. Histopathology indicated it was a keratoacanthoma. In an elderly patient with a history of a progressively growing mass in the nose, a differential diagnosis of malignancy should be ruled out, and histological conformation is essential. To our knowledge, only a very small number of cases of nasal vestibular keratoacanthoma have been reported.

Descriviamo un caso di cheratoacantoma riscontrato a livello del vestibolo nasale in un uomo di 84 anni di età senza storia di esposizione solare. Il paziente presentava una neoformazione nel vestibolo nasale di sinistra comparsa da 8 mesi e progressivamente aumentata di volume. All'esame obiettivo si presentava come una massa esofitica non dolorante a base d'impianto a livello della parete mediale del vestibolo della narice di sinistra. L'esame istologico definitivo poneva diagnosi di cheratoacantoma. In un paziente anziano con storia di neoformazione nasale progressivamente aumentata di volume è necessario escludere la malignità della lesione. Per tale motivo l'esame istologico della lesione è indispensabile. Sulla base della nostra esperienza, sono stati descritti pochi casi di cheratoacantoma del vestibolo nasale.

Keywords: Keratoacanthoma; Nasal vestibule.

PubMed Disclaimer

Figures

Fig. 1.
Fig. 1.
Pre-operative view by nasoendoscopy.
Fig. 2.
Fig. 2.
Micrograph of the keratoacanthoma: (A) Low-power view of the lesion showing solid proliferations of squamous epithelium with intervening fibrovascular stroma. (B) Keratin cysts are present within the squamous epithelium. (C) Formation of a central crater filled with parakeratotic keratin. (D) High-power view of the squamous proliferation where cells show mild atypia.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Schwartz RA. Keratoacanthoma. J Am Acad Dermatol. 1994;30:1–19. - PubMed
    1. Barnetson RS, Halliday GM. Regression in skin tumours: a common phenomenon. Australas J Dermatol. 1997;38(Suppl 1):S63–S65. - PubMed
    1. Patel A, Halliday GM, Cooke BE, et al. Evidence that regression in keratoacanthoma is immunologically mediated: a comparison with squamous cell carcinoma. Br J Dermatol. 1994;131:789–798. - PubMed
    1. Letzel S, Drexler H. Occupational related tumours in tar refinery workers. J Am Acad Dermatol. 1998;39:712–720. - PubMed
    1. Sheyner I, Osipov V. Keratoacanthoma arising after an arthropod sting. J Am Geriatr Soc. 2006;54:1972–1973. - PubMed

Publication types

LinkOut - more resources