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. 2013 Dec 20;8(12):e82310.
doi: 10.1371/journal.pone.0082310. eCollection 2013.

Maternal prepregnancy body mass index and gestational weight gain on pregnancy outcomes

Nan Li  1 , Enqing Liu  2 , Jia Guo  2 , Lei Pan  2 , Baojuan Li  2 , Ping Wang  2 , Jin Liu  2 , Yue Wang  2 , Gongshu Liu  2 , Andrea A Baccarelli  3 , Lifang Hou  4 , Gang Hu  5
Affiliations

Maternal prepregnancy body mass index and gestational weight gain on pregnancy outcomes

Nan Li et al. PLoS One. .

Abstract

Objective: The aim of the present study was to evaluate the single and joint associations of maternal prepregnancy body mass index (BMI) and gestational weight gain (GWG) with pregnancy outcomes in Tianjin, China.

Methods: Between June 2009 and May 2011, health care records of 33,973 pregnant women were collected and their children were measured for birth weight and birth length. The independent and joint associations of prepregnancy BMI and GWG based on the Institute of Medicine (IOM) guidelines with the risks of pregnancy and neonatal outcomes were examined by using Logistic Regression.

Results: After adjustment for all confounding factors, maternal prepregnancy BMI was positively associated with risks of gestational diabetes mellitus (GDM), pregnancy-induced hypertension, caesarean delivery, preterm delivery, large-for-gestational age infant (LGA), and macrosomia, and inversely associated with risks of small-for-gestational age infant (SGA) and low birth weight. Maternal excessive GWG was associated with increased risks of pregnancy-induced hypertension, caesarean delivery, LGA, and macrosomia, and decreased risks of preterm delivery, SGA, and low birth weight. Maternal inadequate GWG was associated with increased risks of preterm delivery and SGA, and decreased risks of LGA and macrosomia, compared with maternal adequate GWG. Women with both prepregnancy obesity and excessive GWG had 2.2-5.9 folds higher risks of GDM, pregnancy-induced hypertension, caesarean delivery, LGA, and macrosomia compared with women with normal prepregnancy BMI and adequate GWG.

Conclusions: Maternal prepregnancy obesity and excessive GWG were associated with greater risks of pregnancy-induced hypertension, caesarean delivery, and greater infant size at birth. Health care providers should inform women to start the pregnancy with a BMI in the normal weight category and limit their GWG to the range specified for their prepregnancy BMI.

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Conflict of interest statement

Competing Interests: The authors have declared that no competing interests exist.

References

    1. Kim SY, Dietz PM, England L, Morrow B, Callaghan WM (2007) Trends in pre-pregnancy obesity in nine states, 1993–2003. Obesity 15: 986–993. - PubMed
    1. Frederick IO, Williams MA, Sales AE, Martin DP, Killien M (2008) Pre-pregnancy body mass index, gestational weight gain, and other maternal characteristics in relation to infant birth weight. Maternal and child health journal 12: 557–567. - PubMed
    1. Nohr EA, Vaeth M, Baker JL, Sorensen T, Olsen J, et al. (2008) Combined associations of prepregnancy body mass index and gestational weight gain with the outcome of pregnancy. Am J Clin Nutr 87: 1750–1759. - PubMed
    1. Guelinckx I, Devlieger R, Beckers K, Vansant G (2008) Maternal obesity: pregnancy complications, gestational weight gain and nutrition. Obesity reviews : an official journal of the International Association for the Study of Obesity 9: 140–150. - PubMed
    1. Sebire NJ, Jolly M, Harris JP, Wadsworth J, Joffe M, et al. (2001) Maternal obesity and pregnancy outcome: a study of 287,213 pregnancies in London. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 25: 1175–1182. - PubMed

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