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. 2014 Jan;20(1):1-5.
doi: 10.3201/eid2001.120532.

Severe fever with thrombocytopenia syndrome, Shandong Province, China, 2011

Hong-Ling Wen, Li Zhao, Shenyong Zhai, Yuanyuan Chi, Feng Cui, Dongxu Wang, Ling Wang, Zhiyu Wang, Qian Wang, Shoufeng Zhang, Yan Liu, Hao Yu, Xue-Jie Yu

Severe fever with thrombocytopenia syndrome, Shandong Province, China, 2011

Hong-Ling Wen et al. Emerg Infect Dis. 2014 Jan.

Abstract

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease in China. The incidence and clinical and laboratory characteristics of SFTS are not clearly defined. During May 22-October 2, 2011, a total of 24 patients with fever, thrombocytopenia, and leukopenia were clinically diagnosed as having SFTS in Yiyuan County, Shandong Province, China. We conducted laboratory tests for these SFTS patients. SFTS virus (SFTSV) infection was confirmed in 22 patients by using reverse transcription PCR and ELISA by acute-phase and convalescent-phase serum samples. Clinical and laboratory manifestations included fever (100%), gastrointestinal symptoms (91%), myalgia (55%), chills (41%), thrombocytopenia (100%), and leukopenia (95%).

Keywords: China; SFTS; SFTSV; Shandong Province; bunyavirus; clinical characteristics; epidemiology; laboratory characteristics; severe fever with thrombocytopenia syndrome; severe fever with thrombocytopenia syndrome virus; viruses.

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Figures

Figure 1
Figure 1
A) Shandong Province, China (black area) where severe fever with thrombocytopenia syndrome was studied, 2011. B) Yiyuan County (black area) in Shandong Province.
Figure 2
Figure 2
Cases of severe fever with thrombocytopenia syndrome, by month of illness onset, Shandong Province, China, 2011.
See this image and copyright information in PMC

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