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. 2013:2013:645787.
doi: 10.1155/2013/645787. Epub 2013 Nov 27.

Multidrug resistant epididymitis progressing to testicular infarct and orchiectomy

Affiliations

Multidrug resistant epididymitis progressing to testicular infarct and orchiectomy

Nicholas J Farber et al. Case Rep Urol. 2013.

Abstract

Global testicular infarction is a rare sequela of infectious epididymitis, with few reports in the urologic literature since the introduction of fluoroquinolones in the late 1980s. Ischemia occurs secondary to inflammation and edema of the spermatic cord with compression of arterial flow. We report a case of multidrug resistant epididymitis following prostate biopsy that progressed to global testicular infarction requiring orchiectomy. This case highlights the fact that epididymitis does not always follow an indolent pathway to resolution. Progression of pain should prompt early imaging and intervention. It further highlights the potential urologic consequences of the rising prevalence of multidrug resistant bowel flora in the United States, which will increasingly influence the management of presumed uncomplicated epididymitis, whether being primary or postprocedural.

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Figures

Figure 1
Figure 1
Right scrotal ultrasound with color Doppler interrogation at presentation to the ED showing A: right testis with preserved vascularity; B: right epididymis with enlargement and slightly increased vascularity.
Figure 2
Figure 2
Right scrotal ultrasound with color Doppler interrogation on day 7 of hospitalization showing A: right markedly heterogeneous testis with blood flow essentially absent; B: prominent, hyperemic right epididymis.
Figure 3
Figure 3
Orchiectomy specimen demonstrating indurated epididymis and spermatic cord with infarcted testis.

References

    1. Trojian TH, Lishnak TS, Heiman D. Epididymitis and orchitis: an overview. American Family Physician. 2009;79(7):583–587. - PubMed
    1. Luzzi GA, O’Brien TS. Acute epididymitis. BJU International. 2001;87(8):747–755. - PubMed
    1. Minamida S, Satoh T, Tabata K, et al. Prevalence of fluoroquinolone-resistant Escherichia coli before and incidence of acute bacterial prostatitis after prostate biopsy. Urology. 2011;78(6):1235–1239. - PubMed
    1. Qi C, Malczynski M, Schaeffer AJ, et al. Characterization of ciprofloxacin-resistant Escherichia coli isolates among men undergoing evaluation for transrectal ultrasound-guided prostate biopsy: prevalence, clonality, and mechanisms of antimicrobial resistance. The Journal of Urology. 2013;190(6):2026–2032. - PubMed
    1. Marks R, McNeil K. Significance of reversal of diastolic blood flow in the evolution of testicular infarction as a complication of epididymo-orchitis. Journal of Radiology Case Reports. 2009;3(6):21–25. - PMC - PubMed

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