Gastric cancer in young patients
- PMID: 24381753
- PMCID: PMC3870864
- DOI: 10.1155/2013/981654
Gastric cancer in young patients
Abstract
Aim: The aim of this study was to see the clinical, pathological, and demographic profile of young patients with stomach carcinoma besides association with p53.
Patients and methods: Prospective study of young patients with stomach carcinoma from January 2005 to December 2009. A total of 50 patients with age less than 40 years were studied.
Results: Male female ratio was 1 : 1.08 in young patients and 2.5 : 1 in older patients. A positive family history of stomach cancer in the first degree relatives was present in 10% of young patients. Resection was possible only in 50% young patients. 26% young patients underwent only palliative gastrojejunostomy. The most common operation was lower partial gastrectomy in 68%. Amongst the intraoperative findings peritoneal metastasis was seen in 17.4% in young patients. 50% young patients presented in stage IV as per AJCC classification (P value .004; sig.). None of the patients presented as stage 1 disease in young group.
Conclusion: Early detection of stomach carcinoma is very important in all patients but in young patients it is of paramount importance.
References
-
- Llanos O, Butte JM, Crovari F, Duarte I, Guzmán S. Survival of young patients after gastrectomy for gastric cancer. World Journal of Surgery. 2006;30(1):17–20. - PubMed
-
- Fuchs CS, Mayer RJ. Medical progress: gastric carcinoma. New England Journal of Medicine. 1995;333(1):32–41. - PubMed
-
- Theuer CP, De Virgilio C, Keese G, et al. Gastric adenocarcinoma in patients 40 years of age or younger. American Journal of Surgery. 1996;172(5):473–477. - PubMed
-
- Levine MS, Laufer I, Thompson JJ. Carcinoma of the gastric cardia in young people. American Journal of Roentgenology. 1983;140(1):69–72. - PubMed
-
- Rasool MT, Lone MM, Wani ML, Afroz F, Zaffar S, Mohib-ul Haq M. Cancer in Kashmir, India: burden and pattern of disease. Journal of Cancer Research and Therapeutics. 2012;8(2):243–246. - PubMed
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
Research Materials
Miscellaneous