The challenge of pancreatic cancer therapy and novel treatment strategy using engineered mesenchymal stem cells

M R Moniri¹, L-J Dai², G L Warnock¹

Affiliations

¹ Department of Surgery, University of British Columbia, Vancouver BC, Canada.
² 1] Department of Surgery, University of British Columbia, Vancouver BC, Canada [2] Hubei Key Laboratory of Stem Cell Research, Taihe Hospital, Hubei University of Medicine, Shiyan, China.

PMID: 24384772
DOI: 10.1038/cgt.2013.83

Review

The challenge of pancreatic cancer therapy and novel treatment strategy using engineered mesenchymal stem cells

M R Moniri et al. Cancer Gene Ther. 2014 Jan.

. 2014 Jan;21(1):12-23.

doi: 10.1038/cgt.2013.83. Epub 2014 Jan 3.

Authors

M R Moniri¹, L-J Dai², G L Warnock¹

Affiliations

¹ Department of Surgery, University of British Columbia, Vancouver BC, Canada.
² 1] Department of Surgery, University of British Columbia, Vancouver BC, Canada [2] Hubei Key Laboratory of Stem Cell Research, Taihe Hospital, Hubei University of Medicine, Shiyan, China.

PMID: 24384772
DOI: 10.1038/cgt.2013.83

Abstract

Mesenchymal stem cells (MSCs) have attracted significant attention in cancer research as a result of their accessibility, tumor-oriented homing capacity, and the feasibility of auto-transplantation. This review provides a comprehensive overview of current challenges in pancreatic cancer therapy, and we propose a novel strategy for using MSCs as means of delivering anticancer genes to the site of pancreas. We aim to provide a practical platform for the development of MSC-based therapy for pancreatic cancer.

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The challenge of pancreatic cancer therapy and novel treatment strategy using engineered mesenchymal stem cells

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The challenge of pancreatic cancer therapy and novel treatment strategy using engineered mesenchymal stem cells

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