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Randomized Controlled Trial
. 2013 Dec 27;8(12):e84901.
doi: 10.1371/journal.pone.0084901. eCollection 2013.

Impact of low filter resistances on subjective and physiological responses to filtering facepiece respirators

Affiliations
Randomized Controlled Trial

Impact of low filter resistances on subjective and physiological responses to filtering facepiece respirators

Raymond J Roberge et al. PLoS One. .

Abstract

Ten subjects underwent treadmill exercise at 5.6 km/h over one hour while wearing each of three identical appearing, cup-shaped, prototype filtering facepiece respirators that differed only in their filter resistances (3 mm, 6 mm, and 9 mm H2O pressure drop). There were no statistically significant differences between filtering facepiece respirators with respect to impact on physiological parameters (i.e., heart rate, respiratory rate, oxygen saturation, transcutaneous carbon dioxide levels, tympanic membrane temperature), pulmonary function variables (i.e., tidal volume, respiratory rate, volume of carbon dioxide production, oxygen consumption, or ventilation), and subjective ratings (i.e., exertion, thermal comfort, inspiratory effort, expiratory effort and overall breathing comfort). The nominal filter resistances of the prototype filtering facepiece respirators correspond to airflow resistances ranging from 2.1 - 6.6 mm H2O/L/s which are less than, or minimally equivalent to, previously reported values for the normal threshold for detection of inspiratory breathing resistance (6 - 7.6 mm H2O/L/sec). Therefore, filtering facepiece respirators with filter resistances at, or below, this level may not impact the wearer differently physiologically or subjectively from those with filter resistances only slightly above this threshold at low-moderate work rates over one hour.

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Conflict of interest statement

Competing Interests: Caroline M. Ylitalo, PhD, and John M. Sebastian, PhD, declare that they are employees of 3M Corporation, St. Paul, MN, a manufacturer of filtering facepiece respirators. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials. Raymond J. Roberge, MD, Jung-Hyun Kim, PhD, Jeffrey B. Powell, MS, and Ronald E. Shaffer, PhD, are U.S. government employees at the National Personal Protective Technology Laboratory, Pittsburgh, PA. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

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