Outcomes of autotransplanted teeth with complete root formation: a systematic review and meta-analysis

Abstract

Aim: In this review, we assessed clinical outcomes of autotransplanted teeth with complete root formation and the effects of various influencing factors.

Materials and methods: Pubmed, Scopus, Google scholar and a hand search were used to identify prospective and retrospective cohort studies and case series till February 2013. Using multilevel Poisson regression, the annual failure rate (FR), 1-year and 5-year survival rates (SRs), infection-related root resorption rate (RR), ankylosis rate (AR), the influences of systemic antibiotics (SAs), endodontic and splinting modalities and donor tooth morphology were analysed. Failure was defined as a transplant being lost during follow-up.

Results: Twenty-six studies were included. The estimated FR, RR, AR, 1- and 5-year SRs were 2.0%, 2.1%, 1.2%, 98.0% and 90.5%, respectively. The estimated FR was higher in the absence of SA, suture splinting, wire splinting ≤14 days and posterior donors. The estimated RR was higher in the absence of SA, endodontic treatment within post-operative 14 days and anterior/premolar donors. The estimated AR was higher with wire splinting and premolar donors.

Conclusions: Tooth autotransplantation with complete root formation is a favourable treatment with rare FR, RR and AR. However, SAs, endodontic and splinting modalities and tooth morphology seemed to influence the outcomes.

Keywords: complete root formation; meta-analysis; survival; systematic review; tooth autotransplantation.