Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Nov;14(7):468-76.
doi: 10.2174/13892029113146660013.

Cisgenics - a sustainable approach for crop improvement

Affiliations

Cisgenics - a sustainable approach for crop improvement

R S Telem et al. Curr Genomics. 2013 Nov.

Abstract

The implication of molecular biology in crop improvement is now more than three decades old. Not surprisingly, technology has moved on, and there are a number of new techniques that may or may not come under the genetically modified (GM) banner and, therefore, GM regulations. In cisgenic technology, cisgenes from crossable plants are used and it is a single procedure of gene introduction whereby the problem of linkage drag of other genes is overcome. The gene used in cisgenic approach is similar compared with classical breeding and cisgenic plant should be treated equally as classically bred plant and differently from transgenic plants. Therefore, it offers a sturdy reference to treat cisgenic plants similarly as classically bred plants, by exemption of cisgenesis from the current GMO legislations. This review covers the implications of cisgenesis towards the sustainable development in the genetic improvement of crops and considers the prospects for the technology.

Keywords: Cisgenic; Intragene; Linkage drag; Sexually compatible.; Transgenic.

PubMed Disclaimer

Figures

Fig. (1)
Fig. (1)
Comparison between Cisgene and transgene technology (Source: Schouten et al. [5]).

References

    1. Caius Rommens M. All-native DNA transformation: a new approach to plant genetic engineering. Trends in Plant. Sci. 2004;9 (9):457–464. - PubMed
    1. Holtorf H, Guitton M C, Reski R. Plant functional genomics. Naturwissenschaften. 2002;89:235–249. - PubMed
    1. Bernasconi P, Alison Woodworth R, Barbara Rosen A, Mani Subramanian V, Daniel Siehl L. A naturally occurring point mutation confers broad range tolerance to herbicides that target acetolactate synthase. J. Biol. Chem. 1995;270:17381–17385. - PubMed
    1. Jacobsen E, Karaba N. Nataraja.Cisgenics - Facilitating the second green revolution in India by improved traditional plant breeding. Curr. Sci. 2008;94(11): 1365–1366.
    1. Schouten HJ, Krens FA, Jacobsen E. Cisgenic plants are similar to traditionally bred plants: international regulations for genetically modified organisms should be altered to exempt cisgenesis. EMBO Rep. 2006;7:750–753. - PMC - PubMed

LinkOut - more resources