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Review
. 2014 Feb;14(2):456.
doi: 10.1007/s11892-013-0456-y.

Nephropathy in youth and young adults with type 2 diabetes

Carolina Solis-Herrera  1 , Curtis L Triplitt, Jane L Lynch
Affiliations
Review

Nephropathy in youth and young adults with type 2 diabetes

Carolina Solis-Herrera et al. Curr Diab Rep. 2014 Feb.

Abstract

The occurrence and progression of nephropathy associated with early onset type 2 diabetes (T2D) is a consequence of the ongoing epidemic of childhood obesity. Minimal evidence regarding treatment effectiveness of renovascular comorbidities in youth with early onset T2D is available, due to the relatively recent emergence of T2D in youth and young adults. Extrapolation of adult therapy guidelines is not an ideal approach to making therapeutic decisions in this population. Evolving management and intervention strategies are based on accumulating longitudinal data from cohorts of well characterized youth and young adults with T2D. The degree of similarity in histologic findings and disease specific characteristics of kidney disease in patients with early onset T2D and albuminuria compared with affected adults is not well characterized. Early aggressive therapies to minimize the impact of nephropathy are indicated as the evidence for best therapies in youth with T2D are further explored.

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Conflict of interest statement

Conflict of Interest

Carolina Solis-Herrera, Curtis L. Triplitt, and Jane L. Lynch declare that they have no conflict of interest.

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