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. 2014 Feb;6(1):30-5.
doi: 10.4021/jocmr1642w. Epub 2013 Dec 13.

National practice in antibiotic prophylaxis in breast cancer surgery

Aydan Eroglu  1 , Durdu Karasoy  2 , Halil Kurt  3 , Semih Baskan  4
Affiliations

National practice in antibiotic prophylaxis in breast cancer surgery

Aydan Eroglu et al. J Clin Med Res. 2014 Feb.

Abstract

Background: Although breast cancer surgery is regarded as a "clean" surgery, surgical site infection (SSI) rates are higher than expected. There is no consensus regarding the use of antibiotic prophylaxis in elective breast surgery. The nationwide survey was conducted to determine the trend of antibiotic prophylaxis in breast cancer among Turkish surgeons.

Methods: The survey was sent to surgeons who are member of Turkish Surgical Association (TSA) via e-mail from TSA web address. A 15 item web-based survey consisted of surgeon demographics and the use of prophylactic antibiotic in patients with risk factors related to SSI.

Results: The number of completed questionnaires was 245. The most common antibiotic used was first generation of cephalosporins. A majority of respondents indicated that prophylaxis was preferred in patients with high risk of SSI including preoperative chemotherapy or radiotherapy, older age, diabetes mellitus, immunodeficiency, immediate reconstruction (P < 0.05). However, the use of drain did not significantly influence antibiotic prophylaxis (P = 0.091).

Conclusions: The use of prophylactic antibiotic was strongly dependent on the presence of some risk factors; however, the variation in current practice regarding antibiotic prophylaxis demonstrated a lack of its effect on preventing SSI after breast cancer surgery.

Keywords: Antibiotic; Breast cancer; National survey; Prophylaxis; Surgery.

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Figures

Figure 1
Figure 1
Distribution of the antibiotics selected for prophylaxis among surgeons.
Figure 2
Figure 2
The percentages of surgeons using antibiotic prophylaxis for various breast surgical procedures.
See this image and copyright information in PMC

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